BDBM50380140 CHEMBL2011155::carbonic anhydrase (CA) inhibitors, benzenesulphonamide ligand, 10
SMILES NS(=O)(=O)c1cc(ccc1Cl)C(=O)CSc1ncccn1
InChI Key InChIKey=ZHRHWGNFAKOKSF-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 9 hits for monomerid = 50380140
Affinity DataKon: 0.0730M-1s-1Assay Description:Binding affinity to human recombinant CA2 expressed in Escherichia coli assessed as dissociation rate constant after 30 secs by surface plasmon reson...More data for this Ligand-Target Pair
Affinity DataKd: 130nMAssay Description:Binding affinity to human recombinant CA2 expressed in Escherichia coli after 30 secs by surface plasmon resonance assayMore data for this Ligand-Target Pair
Affinity DataKd: 140nMAssay Description:Binding affinity to human recombinant CA2 expressed in Escherichia coli by fluorescence-based thermal shift assayMore data for this Ligand-Target Pair
Affinity DataKd: 330nMAssay Description:Binding affinity to human recombinant carbonic anhydrase-2 by thermal shift assayMore data for this Ligand-Target Pair
Affinity DataKd: 430nMAssay Description:Binding affinity to human recombinant carbonic anhydrase-2 by isothermal titration calorimetry assayMore data for this Ligand-Target Pair
Affinity DataKon: 0.0730M-1s-1Assay Description:Displacement of binding of [3H]-BRL 43694 to 5-hydroxytryptamine 3 receptor in rat cerebral cortexMore data for this Ligand-Target Pair
Affinity DataKd: 1.5nMAssay Description:Binding affinity to human full length His-tagged CA2 (1 to 260 residues) expressed in Escherichia coli BL21(DE3) assessed as intrinsic thermodynamic ...More data for this Ligand-Target Pair
Affinity DataKd: 333nMAssay Description:Binding affinity to human recombinant carbonic anhydrase 2 by thermal shift assayMore data for this Ligand-Target Pair
Affinity DataKoff: 5.50E+5s-1Assay Description:Binding affinity to human recombinant CA2 expressed in Escherichia coli assessed as association rate constant after 30 secs by surface plasmon resona...More data for this Ligand-Target Pair